REG3G

This gene encodes a member of the regenerating islet-derived genes (REG)3 protein family. These proteins are secreted, C-type lectins with a carbohydrate recognition domain and N-terminal signal peptide. The protein encoded by this gene is an antimicrobial lectin with activity against Gram-positive bacteria. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Nov 2014]

Description

Regenerating family member 3 gamma

Tissue specificity

Tissue enriched (pancreas)

Subcell location

Cytosol

Predicted location

Secreted to digestive system

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

2 (79025686 - 79028505)

Ensembl ID

ENSG00000143954  (ver. 103.38)

Orthologs

-

UniProt

Q6UW15

neXtProt

NX_Q6UW15

Human splice variants

Protein structure