UCN2

This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]

Description

Urocortin 2

Tissue specificity

Tissue enhanced (skin , vagina)

Subcell location

Vesicles

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

3 (48561718 - 48563781)

Ensembl ID

ENSG00000145040  (ver. 103.38)

Orthologs

Mouse Ucn2: ENSMUSG00000049699

UniProt

Q96RP3

neXtProt

NX_Q96RP3

Human splice variants
Mouse splice variants

Protein structure