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Protein structure
PAM
Peptidylglycine alpha-amidating monooxygenasePAL, PHM
This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Top validated antibodies |
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| Atlas Antibodies |  HPA042260 |
Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | PA5-59929 |
1 references | Polyclonal |
WB
ICC
IHC
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| Proteintech Group | 26972-1-AP |
1 references | Polyclonal |
WB
EL
IHC
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| Cusabio Biotech Co., Ltd | CSB-PA017417LA01HU |
Polyclonal |
WB
EL
ICC
IHC
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| Biorbyt | orb416879 |
Polyclonal |
WB
EL
ICC
IHC
|
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