ADAMTS19

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008]

Description

ADAM metallopeptidase with thrombospondin type 1 motif 19

Tissue specificity

Tissue enhanced (cervix, endometrium , smooth muscle)

Subcell location

Vesicles, Midbody

Predicted location

Secreted to extracellular matrix

Protein family

Predicted secreted proteins

Chromosome

5 (129460281 - 129738683)

Ensembl ID

ENSG00000145808  (ver. 103.38)

Orthologs

Mouse Adamts19: ENSMUSG00000053441

UniProt

 

neXtProt

 

Human splice variants
Mouse splice variants

Protein structure