Tissue expression
Cell line expression
Protein structure
IGFBP3
Insulin like growth factor binding protein 3BP-53, IBP3
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 10189-2-AP | 30 references | Polyclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | AF675 | 10 references | Polyclonal |
WB
IHC
BN
|
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R&D Systems | AF675 | 9 references | Polyclonal |
WB
IHC
BN
|
|
antibodies-online | ABIN686497 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Boster Biological Technology | PB9710 | 2 references | Polyclonal |
WB
EL
IHC
|
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