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SHROOM2
Shroom family member 2APXL
This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Top validated antibodies |
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| GeneTex |  GTX100055 |
1 references | Polyclonal |
WB
IHC
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| Novus Biologicals | NB100-1350 |
1 references | Polyclonal |
EL
IHC
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| NSJ Bioreagents | RQ7652 |
Polyclonal |
WB
EL
FC
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| Cusabio Biotech Co., Ltd | CSB-PA622684LA01HU |
Polyclonal |
EL
ICC
IHC
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| Biorbyt | orb1402072 |
Polyclonal |
WB
EL
FC
|
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