Tissue expression
Cell line expression
Protein structure
NDUFB9
NADH:ubiquinone oxidoreductase subunit B9B22, LYRM3, UQOR22
The protein encoded by this gene is a subunit of the mitochondrial oxidative phosphorylation complex I (nicotinamide adenine dinucleotide: ubiquinone oxidoreductase). Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q. Complex I deficiency is the most common defect found in oxidative phosphorylation disorders and results in a range of conditions, including lethal neonatal disease, hypertrophic cardiomyopathy, liver disease, and adult-onset neurodegenerative disorders. Pseudogenes of this gene are found on chromosomes five, seven and eight. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Top validated antibodies |
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LSBio | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
Monoclonal |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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Biorbyt | ![]() |
Recombinant |
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Novus Biologicals | ![]() |
Polyclonal |
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