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Protein structure
EI24
EI24 autophagy associated transmembrane proteinEPG4, PIG8, TP53I8
This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014]
Top validated antibodies |
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| Proteintech Group |  20456-1-AP |
3 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | NBP2-13949 |
1 references | Polyclonal |
WB
ICC
IHC
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| antibodies-online | ABIN1450056 |
1 references | Polyclonal |
WB
EL
IHC
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| LSBio | LS-B7502 |
Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-62296 |
Polyclonal |
WB
ICC
IHC
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