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Cell line expression
Protein structure
LATS2
Large tumor suppressor kinase 2This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  20276-1-AP |
31 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| LSBio | LS-C98953 |
Polyclonal |
WB
IHC
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| NovoPro Bioscience Inc. | 112157 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| FineTest Biotech | FNab04709 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Biorbyt | orb395262 |
Polyclonal |
WB
EL
ICC
IHC
FC
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