DLG2

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. [provided by RefSeq, Dec 2008]

Description

Discs large MAGUK scaffold protein 2

Tissue specificity

Tissue enhanced (brain)

Subcell location

Vesicles, Plasma membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

11 (83455012 - 85627922)

Ensembl ID

ENSG00000150672  (ver. 103.38)

Orthologs

Mouse Dlg2: ENSMUSG00000052572

UniProt

Q15700

neXtProt

NX_Q15700

Human splice variants
Mouse splice variants

Protein structure