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CalpastatinThe protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Top validated antibodies |
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| Proteintech Group |  12250-1-AP |
4 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | 12250-1-AP |
Polyclonal |
WB
ICC
IP
IHC
FC
OA
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| LSBio | LS-C155216 |
Polyclonal |
WB
IHC
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| NovoPro Bioscience Inc. | 108904 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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| Novus Biologicals | NB120-5582 |
1 references | Monoclonal |
WB
ICC
IHC
|
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