ADPRHL1

ADP-ribosylation is a reversible posttranslational modification used to regulate protein function. ADP-ribosyltransferases (see ART1; MIM 601625) transfer ADP-ribose from NAD+ to the target protein, and ADP-ribosylhydrolases, such as ADPRHL1, reverse the reaction (Glowacki et al., 2002 [PubMed 12070318]). [supplied by OMIM, Mar 2008]

Description

ADP-ribosylhydrolase like 1

Tissue specificity

Group enriched (heart muscle, skeletal muscle, tongue)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

13 (113399610 - 113453524)

Ensembl ID

ENSG00000153531  (ver. 103.38)

Orthologs

Mouse Adprhl1: ENSMUSG00000031448

UniProt

Q8NDY3

neXtProt

NX_Q8NDY3

Human splice variants
Mouse splice variants

Protein structure