Tissue expression
Cell line expression
Protein structure
ZUP1
Zinc finger containing ubiquitin peptidase 1C6orf113, dJ412I7.3, ZUFSP
This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. ""endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018]
Top validated antibodies |
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LSBio | LS-C830384 | Polyclonal |
WB
EL
IHC
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Biorbyt | orb1279368 | Polyclonal |
WB
EL
IHC
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antibodies-online | ABIN2844310 | 1 references | Polyclonal |
WB
|
|
Atlas Antibodies | HPA044426 | Polyclonal |
ICC
IHC |
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Invitrogen Antibodies | PA5-60709 | Polyclonal |
ICC
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider