Tissue expression
Cell line expression
Protein structure
OTULIN
OTU deubiquitinase with linear linkage specificityFAM105B, FLJ34884
This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016]
Top validated antibodies |
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Boster Biological Technology | A07938-1 | 4 references | Polyclonal |
WB
EL
ICC
IHC
FC
|
|
Atlas Antibodies | HPA051074 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
NSJ Bioreagents | RQ6146 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Novus Biologicals | NBP2-14722 | 1 references | Polyclonal |
WB
ICC
IP
IHC |
|
Biorbyt | orb670317 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider