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PDE1C
Phosphodiesterase 1CHcam3
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| GeneTex |  GTX14602 |
1 references | Polyclonal |
WB
ICC
IP
IHC
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| antibodies-online | ABIN5683757 |
1 references | Polyclonal |
WB
ICC
IP
IHC
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| Novus Biologicals | NB300-672-0.05mg |
Polyclonal |
WB
EL
ICC
IP
IHC
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| Proteintech Group | 13785-1-AP |
2 references | Polyclonal |
WB
EL
IP
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| Invitrogen Antibodies | PA5-115728 |
Polyclonal |
WB
ICC
IHC
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