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SIM2
SIM bHLH transcription factor 2bHLHe15, MGC119447, SIM
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Top validated antibodies |
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| Proteintech Group |  21069-1-AP |
1 references | Polyclonal |
WB
EL
IP
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| FineTest Biotech | FNab07869 |
Polyclonal |
WB
EL
IP
IHC
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| Biorbyt | orb631190 |
Polyclonal |
WB
EL
IP
IHC
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| Invitrogen Antibodies | 21069-1-AP |
Polyclonal |
WB
IP
OA
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| Novus Biologicals | NBP1-68864 |
1 references | Polyclonal |
WB
EL
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