Tissue expression
Cell line expression
Protein structure
THEM4
Thioesterase superfamily member 4CTMP
Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies | Polyclonal |
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| Proteintech Group | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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| GeneTex | Polyclonal |
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| antibodies-online | 3 references | Polyclonal |
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