Tissue expression
Cell line expression
Protein structure
IKZF3
IKAROS family zinc finger 3Aiolos, ZNFN1A3
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
Top validated antibodies |
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Proteintech Group | 19055-1-AP | 2 references | Polyclonal |
WB
EL
ICC
IHC |
|
antibodies-online | ABIN394045 | 5 references | Monoclonal |
EL
ICC
IHC
|
|
Cell Signaling Technology, Inc | 15103 | Monoclonal |
WB
IP
IHC
FC
ChIP
|
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Invitrogen Antibodies | MA5-42889 | Monoclonal |
WB
ICC
IP
IHC |
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Biorbyt | orb1819469 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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