Tissue expression
Cell line expression
Protein structure
GRIN2C
Glutamate ionotropic receptor NMDA type subunit 2CGluN2C, NMDAR2C
This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Top validated antibodies |
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Novus Biologicals | NB300-107 | 3 references | Polyclonal |
WB
ICC
IP
|
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Invitrogen Antibodies | OPA1-04020 | 4 references | Polyclonal |
WB
IP
OA
|
|
Antibodies Incorporated / NeuroMab | 73-411 | Monoclonal |
WB
ICC
IHC
|
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antibodies-online | ABIN152456 | 3 references | Polyclonal |
WB
ICC
IP
|
|
Cusabio Biotech Co., Ltd | CSB-PA009914LA01HU | Polyclonal |
EL
ICC
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider