FCRL4

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]

Description

Fc receptor like 4

Tissue specificity

Tissue enriched (lymphoid tissue)

Predicted location

Membrane

Protein family

Cancer-related genes
CD markers
Disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins

Chromosome

1 (157573747 - 157598085)

Ensembl ID

ENSG00000163518  (ver. 103.38)

Orthologs

-

UniProt

Q96PJ5

neXtProt

NX_Q96PJ5

Human splice variants

Protein structure