Tissue expression
Cell line expression
Protein structure
UCN
UrocortinUI, UROC
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family. The encoded preproprotein is proteolytically processed to generate the mature peptide, an endogenous ligand for both corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. In the brain this peptide may be responsible for the effects of stress on appetite. This peptide may also play a role in mood disorders, neurodegeneration, and skeletal system disorders. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin-2. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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| Novus Biologicals | 2 references | Monoclonal |
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| R&D Systems | 1 references | Monoclonal |
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| Proteintech Group | 1 references | Polyclonal |
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| Boster Biological Technology | 1 references | Polyclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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