Tissue expression
Cell line expression
Protein structure
H2AZ1
H2A.Z variant histone 1H2A.Z, H2AFZ, H2AZ
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | GTX108273 | Polyclonal |
WB
ICC
IP
IHC
ChIP
|
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LSBio | LS-C185966 | Polyclonal |
WB
ICC
IP
IHC |
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OriGene | TA308893 | Polyclonal |
WB
ICC
IP
IHC
OA
|
||
antibodies-online | ABIN2438246 | Polyclonal |
WB
ICC
IP
IHC
ChIP
|
||
Novus Biologicals | NBP2-54619 | Polyclonal |
WB
EL
ICC
ChIP
OA
|
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Supportive data in Antibodypedia
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Recommended by provider