LSM6

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. [supplied by OMIM, Apr 2004]

Description

LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated

Tissue specificity

Low tissue specificity

Subcell location

Actin filaments

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

4 (146175703 - 146200000)

Ensembl ID

ENSG00000164167  (ver. 103.38)

Orthologs

Mouse Lsm6: ENSMUSG00000031683

UniProt

P62312

neXtProt

NX_P62312

Human splice variants
Mouse splice variants

Protein structure