TAGAP

This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]

Description

T cell activation RhoGTPase activating protein

Tissue specificity

Tissue enhanced (bone marrow, lymphoid tissue)

Subcell location

Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

6 (159034468 - 159045152)

Ensembl ID

ENSG00000164691  (ver. 103.38)

Orthologs

-

UniProt

Q8N103

neXtProt

NX_Q8N103

Human splice variants

Protein structure