SNAPC4

This gene encodes the largest subunit of the small nuclear RNA-activating protein (SNAP) complex. The encoded protein contains a Myb DNA-binding domain, and is essential for RNA polymerase II and III polymerase transcription from small nuclear RNA promoters. A mutation in this gene is associated with ankylosing spondylitis. [provided by RefSeq, Jul 2016]

Description

Small nuclear RNA activating complex polypeptide 4

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Nuclear membrane, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

9 (136375577 - 136400168)

Ensembl ID

ENSG00000165684  (ver. 103.38)

Orthologs

Mouse Snapc4: ENSMUSG00000036281

UniProt

Q5SXM2

neXtProt

NX_Q5SXM2

Human splice variants
Mouse splice variants

Protein structure