Tissue expression
Cell line expression
Protein structure
SMPD1
Sphingomyelin phosphodiesterase 1ASM
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
Top validated antibodies |
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| Proteintech Group | 16 references | Polyclonal |
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| antibodies-online | 1 references | Polyclonal |
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| LSBio | Monoclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| Novus Biologicals | Polyclonal |
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