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Protein structure
KIF7
Kinesin family member 7JBTS12
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011]
Top validated antibodies |
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| Proteintech Group |  24693-1-AP |
3 references | Polyclonal |
WB
EL
IP
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| Biorbyt | orb919883 |
Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | 24693-1-AP |
Polyclonal |
WB
IP
OA
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| NovoPro Bioscience Inc. | 112051 |
Polyclonal |
WB
EL
IP
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| Wuhan Fine Biotech Co., Ltd. | FNab04570 |
Polyclonal |
WB
EL
IP
|
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