Tissue expression
Cell line expression
Protein structure
CDC42EP5
CDC42 effector protein 5Borg3, CEP5
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013]
Top validated antibodies |
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Novus Biologicals | NBP1-91773 | Polyclonal |
WB
ICC
IHC
|
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Boster Biological Technology | A14184-1 | Polyclonal |
WB
EL
IHC
|
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St John's Laboratory | STJ92176 | Polyclonal |
WB
EL
ICC
IHC |
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Cusabio Biotech Co., Ltd | CSB-PA001512 | Polyclonal |
WB
EL
IHC
|
||
Affinity Biosciences | DF3911 | Polyclonal |
WB
EL
ICC
|
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