Tissue expression
Cell line expression
Protein structure
SPINT2
Serine peptidase inhibitor, Kunitz type 2HAI-2, Kop
This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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| Novus Biologicals | 1 references | Polyclonal |
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| LSBio | Polyclonal |
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| antibodies-online | Polyclonal |
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| R&D Systems | 2 references | Polyclonal |
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| Everest Biotech | Polyclonal |
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