Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
CTNND2
Catenin delta 2GT24, NPRAP
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Top validated antibodies |
|||||
| Novus Biologicals |  H00001501-M01 |
1 references | Monoclonal |
WB
EL
ICC
IHC
|
|
| LSBio | LS-C167134 |
Polyclonal |
WB
IHC
|
||
| antibodies-online | ABIN951062 |
5 references | Polyclonal |
WB
IHC
|
|
| Abnova Corporation | H00001501-M01 |
1 references | Monoclonal |
WB
EL
|
|
| NovoPro Bioscience Inc. | 124444 |
Polyclonal |
WB
EL
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider