SLN

Sarcoplasmic reticulum Ca(2+)-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of Ca(2+) from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. This gene encodes a small proteolipid that regulates several sarcoplasmic reticulum Ca(2+)-ATPases. The transmembrane protein interacts with Ca(2+)-ATPases and reduces the accumulation of Ca(2+) in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis. [provided by RefSeq, Jul 2008]

Description

Sarcolipin

Tissue specificity

Group enriched (skeletal muscle, tongue)

Subcell location

Microtubules

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Transporters

Chromosome

11 (107707378 - 107719693)

Ensembl ID

ENSG00000170290  (ver. 103.38)

Orthologs

-

UniProt

O00631

neXtProt

NX_O00631

Human splice variants

Protein structure