NUDT9

The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Description

Nudix hydrolase 9

Tissue specificity

Low tissue specificity

Subcell location

Nuclear membrane, Nuclear bodies, Cell Junctions, Mitochondria

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

4 (87422573 - 87459455)

Ensembl ID

ENSG00000170502  (ver. 103.38)

Orthologs

Mouse Nudt9: ENSMUSG00000029310

UniProt

Q9BW91

neXtProt

NX_Q9BW91

Human splice variants
Mouse splice variants

Protein structure