Tissue expression
Cell line expression
Protein structure
STAT2
Signal transducer and activator of transcription 2STAT113
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44. [provided by RefSeq, Aug 2020]
Top validated antibodies |
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Invitrogen Antibodies | 44-362G | 2 references | Polyclonal |
WB
ICC
IP
IHC
FC
ChIP
OA
|
|
Proteintech Group | 16674-1-AP | 8 references | Polyclonal |
WB
EL
IP
IHC |
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GeneTex | GTX103117 | 3 references | Polyclonal |
WB
IP
IHC
|
|
Cell Signaling Technology, Inc | 72604 | Monoclonal |
WB
ICC
IP
FC
ChIP
|
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antibodies-online | ABIN393838 | Monoclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider