Tissue expression
Cell line expression
Protein structure
TSEN34
TRNA splicing endonuclease subunit 34LENG5, SEN34, SEN34L
This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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| Atlas Antibodies | Polyclonal |
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| NSJ Bioreagents | Polyclonal |
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| Biorbyt | Polyclonal |
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| Invitrogen Antibodies | Monoclonal |
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| Novus Biologicals | Polyclonal |
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