Tissue expression
Cell line expression
Protein structure
EXOSC1
Exosome component 1CGI-108, CSL4, Csl4p, hCsl4p, p13, SKI4, Ski4p
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Top validated antibodies |
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| Proteintech Group | 2 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Novus Biologicals | Monoclonal |
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| Abnova Corporation | Monoclonal |
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| antibodies-online | Polyclonal |
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