Tissue expression
Cell line expression
Protein structure
CCL11
C-C motif chemokine ligand 11eotaxin, MGC22554, SCYA11
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
Top validated antibodies |
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R&D Systems | AF-420-NA | 22 references | Polyclonal |
WB
EL
IHC
BN |
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Novus Biologicals | AF-420-NA | 22 references | Polyclonal |
WB
IHC
BN
|
|
Proteintech Group | 11786-1-AP | 2 references | Polyclonal |
WB
EL
IHC
|
|
Invitrogen Antibodies | 500-P41-1MG | 4 references | Polyclonal |
WB
EL |
|
GeneTex | GTX31166 | Polyclonal |
WB
EL
IHC
BN |
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