Tissue expression
Cell line expression
Protein structure
AZU1
Azurocidin 1AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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NSJ Bioreagents | RQ6825 | Polyclonal |
WB
EL
IHC
FC |
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Novus Biologicals | H00000566-B01P | Polyclonal |
WB
ICC
IHC
|
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Abnova Corporation | H00000566-B01P | Polyclonal |
WB
ICC
IHC
|
||
Biorbyt | orb1098043 | Polyclonal |
WB
EL
IHC
FC |
||
R&D Systems | AF2200 | 2 references | Polyclonal |
WB
IP |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider