Tissue expression
Cell line expression
Protein structure
ADCY5
Adenylate cyclase 5AC5
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Top validated antibodies |
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| LSBio | Polyclonal |
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| Antibodies.com | Polyclonal |
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| Novus Biologicals | 1 references | Monoclonal |
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| antibodies-online | 1 references | Polyclonal |
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| Cusabio Biotech Co., Ltd | Polyclonal |
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