Tissue expression
Cell line expression
Protein structure
OLR1
Oxidized low density lipoprotein receptor 1CLEC8A, LOX-1, SCARE1
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Top validated antibodies |
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| Proteintech Group | 39 references | Polyclonal |
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| antibodies-online | 6 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Novus Biologicals | 7 references | Monoclonal |
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| R&D Systems | 7 references | Monoclonal |
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