NLRP13

This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Description

NLR family pyrin domain containing 13

Tissue specificity

Not detected

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

19 (55891699 - 55932336)

Ensembl ID

ENSG00000173572  (ver. 103.38)

Orthologs

-

UniProt

Q86W25

neXtProt

NX_Q86W25

Human splice variants

Protein structure