Tissue expression
Cell line expression
Protein structure

RTTN

Rotatin
DKFZP434G145 
This gene encodes a large protein whose specific function is unknown. Absence of the orthologous protein in mouse results in embryonic lethality with deficient axial rotation, abnormal differentiation of the neural tube, and randomized looping of the heart tube during development. In human, mutations in this gene are associated with polymicrogyria with seizures. In human fibroblasts this protein localizes at the ciliary basal bodies. Given the intracellular localization of this protein and the phenotypic effects of mutations, this gene is suspected of playing a role in the maintenance of normal ciliary structure which in turn effects the developmental process of left-right organ specification, axial rotation, and perhaps notochord development. [provided by RefSeq, Jan 2013]
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30 antibodies from 10 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
2 antibodies
Novus Biologicals
4 antibodies
Invitrogen Antibodies
3 antibodies
antibodies-online
4 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
Biorbyt
4 antibodies
Abnova Corporation
2 antibodies
Atlas Antibodies
2 antibodies
Creative Diagnostics
3 antibodies
OriGene
2 antibodies