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TCIM
Transcriptional and immune response regulatorC8orf4, hTC-1, TC-1, TC1
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]
Top validated antibodies |
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| Proteintech Group |  26279-1-AP |
1 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | NBP1-81657 |
1 references | Polyclonal |
ICC
IHC
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| LSBio | LS-C830553 |
Polyclonal |
EL
IHC
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| Invitrogen Antibodies | 26279-1-AP |
Polyclonal |
WB
IHC
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| Boster Biological Technology | A31995 |
Polyclonal |
WB
IHC
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