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Protein structure
TOP3A
DNA topoisomerase III alphaTOP3, ZGRF7
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Top validated antibodies |
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| Proteintech Group |  14525-1-AP |
27 references | Polyclonal |
WB
EL
IP
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| Invitrogen Antibodies | 14525-1-AP |
Polyclonal |
WB
IP
OA
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| NovoPro Bioscience Inc. | 116249 |
Polyclonal |
WB
EL
IP
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| Affinity Biosciences | DF3265 |
Polyclonal |
WB
EL
ICC
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| FineTest Biotech | FNab08870 |
Polyclonal |
WB
EL
IP
|
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