Tissue expression
Cell line expression
Protein structure
SELENOW
Selenoprotein WSELW, SEPW1
This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is highly expressed in skeletal muscle, heart and brain. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Studies in mouse show that this selenoprotein is involved in muscle growth and differentiation, and in the protection of neurons from oxidative stress during neuronal development. A retroprocessed pseudogene of this locus has been identified on chromosome 1. [provided by RefSeq, Aug 2017]
Top validated antibodies |
|||||
GeneTex | GTX48717 | 1 references | Polyclonal |
WB
EL
IP
|
|
Novus Biologicals | NBP1-49599 | 1 references | Polyclonal |
WB
EL
IP
|
|
Biorbyt | orb2206801 | Polyclonal |
WB
ICC
IP
IHC |
||
LSBio | LS-C396507 | Polyclonal |
EL
IHC |
||
Abnova Corporation | PAB11324 | 3 references | Polyclonal |
WB
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider