DEFB123

Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. This antimicrobial protein is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20q11.1. Two transcript variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Nov 2014]

Description

Defensin beta 123

Tissue specificity

Group enriched (epididymis, testis)

Predicted location

Secreted in other tissues

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins
Protein evidence (Kim et al 2014)

Chromosome

20 (31440632 - 31450257)

Ensembl ID

ENSG00000180424  (ver. 103.38)

Orthologs

Mouse Defb36: ENSMUSG00000044863

UniProt

Q8N688

neXtProt

NX_Q8N688

Human splice variants
Mouse splice variants

Protein structure