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NQO1
NAD(P)H quinone dehydrogenase 1DHQU, DIA4, DTD, NMOR1, QR1
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  11451-1-AP |
149 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Atlas Antibodies | HPA007308 |
4 references | Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | MA1-16672 |
2 references | Monoclonal |
WB
ICC
IP
IHC
FC
OA
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| Novus Biologicals | NB200-209 |
39 references | Monoclonal |
WB
ICC
IP
IHC
FC
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| antibodies-online | ABIN152344 |
27 references | Monoclonal |
WB
ICC
IP
IHC
FC
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