H2AW

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]

Description

H2A.W histone

Tissue specificity

Tissue enhanced (adrenal gland)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins

Chromosome

1 (228456979 - 228457873)

Ensembl ID

ENSG00000181218  (ver. 103.38)

Orthologs

Mouse H2aw: ENSMUSG00000078851

UniProt

Q7L7L0

neXtProt

NX_Q7L7L0

Human splice variants
Mouse splice variants

Protein structure