Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
CLDN7
Claudin 7CEPTRL2, CPETRL2, Hs.84359
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, May 2010]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  37-4800 |
17 references | Monoclonal |
WB
EL
ICC
IP
IHC
OA
|
|
| antibodies-online | ABIN951552 |
3 references | Polyclonal |
WB
IHC
FC
|
|
| Proteintech Group | 10118-1-AP |
4 references | Polyclonal |
WB
EL
IHC
|
|
| Biorbyt | orb738379 |
Polyclonal |
WB
EL
ICC
IHC
FC
|
||
| Boster Biological Technology | A03851-1 |
Polyclonal |
WB
ICC
IP
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider