ASB18

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Feb 2017]

Description

Ankyrin repeat and SOCS box containing 18

Tissue specificity

Group enriched (brain, heart muscle, skeletal muscle)

Subcell location

Nucleoli, Mitochondria

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Kim et al 2014)

Chromosome

2 (236194872 - 236264409)

Ensembl ID

ENSG00000182177  (ver. 103.38)

Orthologs

Mouse Asb18: ENSMUSG00000067081

UniProt

Q6ZVZ8

neXtProt

NX_Q6ZVZ8

Human splice variants
Mouse splice variants

Protein structure