DDX28

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is intronless. It encodes an RNA-dependent ATPase. The encoded protein is localized in the mitochondria and the nucleus, and can be transported between the mitochondria and the nucleus. [provided by RefSeq, Jul 2008]

Description

DEAD-box helicase 28

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli, Mitochondria, Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16 (68020916 - 68023232)

Ensembl ID

ENSG00000182810  (ver. 103.38)

Orthologs

Mouse Ddx28: ENSMUSG00000045538

UniProt

Q9NUL7

neXtProt

NX_Q9NUL7

Human splice variants
Mouse splice variants

Protein structure